5CCG

Structure of the Ca2+-bound synaptotagmin-1 SNARE complex (long unit cell form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, G (A, G)	Vesicle-associated membrane protein 2	polymer	63	7231.1	2	UniProt (P63045) Pfam (PF00957)	Rattus norvegicus (Rat)	VAMP-2,Synaptobrevin-2
2	B, H (B, H)	Syntaxin-1A	polymer	67	7838.0	2	UniProt (P32851) Pfam (PF05739)	Rattus norvegicus (Rat)	Neuron-specific antigen HPC-1,Synaptotagmin-associated 35 kDa protein,P35A
3	C, I (C, I)	Synaptosomal-associated protein 25	polymer	77	9030.1	2	UniProt (P60881)	Rattus norvegicus (Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
4	D, J (D, J)	Synaptosomal-associated protein 25	polymer	65	7471.4	2	UniProt (P60881)	Rattus norvegicus (Rat)	SNAP-25,Super protein,SUP,Synaptosomal-associated 25 kDa protein
5	E, F, K (E, F, K)	Synaptotagmin-1	polymer	281	32247.2	3	UniProt (P21707) Pfam (PF00168)	Rattus norvegicus (Rat)	Synaptotagmin I,SytI,p65
6	AA, BA, CA, DA, L... (K, A, C, D, E...)	CALCIUM ION	non-polymer		40.1	19	Chemie (CA)
7	EA, FA, GA, HA, IA... (A, B, D, E, F...)	water	water		18.0	18	Chemie (HOH)

Sequence modifications

A, G: 28 - 89 (UniProt: P63045)

PDB	External Database	Details
Gly 27	-	expression tag

B, H: 191 - 256 (UniProt: P32851)

PDB	External Database	Details
Met 190	-	initiating methionine

D, J: 141 - 204 (UniProt: P60881)

PDB	External Database	Details
Met 140	-	initiating methionine

Contents of the asymmetric unit

Polymers	Number of chains	11
	Total formula weight	159882.6
Non-Polymers*	Number of molecules	19
	Total formula weight	761.5
All*	Total formula weight	160644.1

*Water molecules are not included.