5CCB
Crystal structure of human m1A58 methyltransferase in a complex with tRNA3Lys and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | polymer | 289 | 31420.6 | 1 | UniProt (Q96FX7) Pfam (PF08704) | Homo sapiens (Human) | tRNA(m1A58)-methyltransferase subunit TRMT61A,tRNA(m1A58)MTase subunit TRMT61A |
| 2 | B (B) | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | polymer | 497 | 55883.3 | 1 | UniProt (Q9UJA5) Pfam (PF04189) | Homo sapiens (Human) | tRNA(m1A58)-methyltransferase subunit TRM6,tRNA(m1A58)MTase subunit TRM6 |
| 3 | C (N) | tRNA3Lys | polymer | 77 | 24792.7 | 1 | GenBank (339572) | Homo sapiens | |
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525) | |||
| 5 | E (N) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) PubChem (923) | |||
| 6 | F, G, H (A, B, N) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
N: 0 - 73 (GenBank: 339572)
| PDB | External Database | Details |
|---|---|---|
| C 74 | - | insertion |
| C 75 | - | insertion |
| A 76 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112096.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 407.4 | |
| All* | Total formula weight | 112504.0 |
