5CCB
Crystal structure of human m1A58 methyltransferase in a complex with tRNA3Lys and SAH
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A | polymer | 289 | 31420.6 | 1 | UniProt (Q96FX7) Pfam (PF08704) | Homo sapiens (Human) | tRNA(m1A58)-methyltransferase subunit TRMT61A,tRNA(m1A58)MTase subunit TRMT61A |
| 2 | B (B) | tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6 | polymer | 497 | 55883.3 | 1 | UniProt (Q9UJA5) Pfam (PF04189) | Homo sapiens (Human) | tRNA(m1A58)-methyltransferase subunit TRM6,tRNA(m1A58)MTase subunit TRM6 |
| 3 | C (N) | tRNA3Lys | polymer | 77 | 24792.7 | 1 | GenBank (339572) | Homo sapiens | |
| 4 | D (A) | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | E (N) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F, G, H (A, B, N) | water | water | 18.0 | 416 | Chemie (HOH) |
Sequence modifications
N: 0 - 73 (GenBank: 339572)
| PDB | External Database | Details |
|---|---|---|
| C 74 | - | insertion |
| C 75 | - | insertion |
| A 76 | - | insertion |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 112096.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 407.4 | |
| All* | Total formula weight | 112504.0 |
