5CBW
Human Cyclophilin D Complexed with Inhibitor.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Peptidyl-prolyl cis-trans isomerase F, mitochondrial | polymer | 165 | 17783.3 | 1 | UniProt (P30405) Pfam (PF00160) | Homo sapiens (Human) | PPIase F,Cyclophilin D,CypD,Cyclophilin F,Mitochondrial cyclophilin,CyP-M,Rotamase F |
| 2 | B, C (A) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 3 | D (A) | FORMIC ACID | non-polymer | 46.0 | 1 | Chemie (FMT) | |||
| 4 | E (A) | TETRAETHYLENE GLYCOL | non-polymer | 194.2 | 1 | Chemie (PG4) | |||
| 5 | F (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 1 | Chemie (PGE) | |||
| 6 | G (A) | ethyl N-{[4-(acetylamino)benzyl]carbamoyl}glycinate | non-polymer | 293.3 | 1 | Chemie (4ZO) | |||
| 7 | H (A) | water | water | 18.0 | 161 | Chemie (HOH) |
Sequence modifications
A: 2 - 165 (UniProt: P30405)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
| Ile 133 | Lys 175 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17783.3 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 761.9 | |
| All* | Total formula weight | 18545.3 |
