5CAV
EGFR kinase domain with compound 41a
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Epidermal growth factor receptor | polymer | 331 | 37649.4 | 1 | UniProt (P00533) Pfam (PF07714) In PDB | Homo sapiens (Human) | Proto-oncogene c-ErbB-1,Receptor tyrosine-protein kinase erbB-1 |
2 | A | (1R)-1-{6-({2-[(3R,4S)-3-fluoro-4-methoxypiperidin-1-yl]pyrimidin-4-yl}amino)-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-imidazo[4,5-c]pyridin-2-yl}ethanol | non-polymer | 483.5 | 1 | Chemie (4ZQ) | |||
3 | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 695 - 1022 (UniProt: P00533)
PDB | External Database | Details |
---|---|---|
Gly 694 | - | expression tag |
Asn 1023 | - | expression tag |
Ser 1024 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 37649.4 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 483.5 | |
All* | Total formula weight | 38132.9 |