5C8E
Crystal structure of Thermus thermophilus CarH bound to adenosylcobalamin and a 26-bp DNA segment
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Light-dependent transcriptional regulator CarH | polymer | 305 | 33323.3 | 8 | UniProt (Q746J7) | Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) | |
| 2 | I, K (I, K) | 26-mer DNA segment containing the CarH operator sequence (antisense strand) | polymer | 26 | 7998.2 | 2 | Thermus thermophilus HB27 | ||
| 3 | J, L (J, L) | 26-mer DNA segment containing the CarH operator sequence (sense strand) | polymer | 26 | 7972.2 | 2 | Thermus thermophilus HB27 | ||
| 4 | AA, M, O, Q, S... (H, A, B, C, D...) | COBALAMIN | non-polymer | 1330.4 | 8 | Chemie (B12) | |||
| 5 | BA, N, P, R, T... (H, A, B, C, D...) | 5'-DEOXYADENOSINE | non-polymer | 251.2 | 8 | Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (71678) PubChem (23638944) PubChem (439182) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (23615209) PubChem (449044) PubChem (40467849) PubChem (1277776) PubChem (57115448) PubChem (59731278) PubChem (6398669) PubChem (6928544) PubChem (90321697) PubChem (676784) PubChem (12827542) PubChem (6541038) PubChem (121275112) PubChem (124363198) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 285 (UniProt: Q746J7)
| PDB | External Database | Details |
|---|---|---|
| Met -19 | - | initiating methionine |
| Gly -18 | - | expression tag |
| Ser -17 | - | expression tag |
| Ser -16 | - | expression tag |
| His -15 | - | expression tag |
| His -14 | - | expression tag |
| His -13 | - | expression tag |
| His -12 | - | expression tag |
| His -11 | - | expression tag |
| His -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Ser -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Leu -6 | - | expression tag |
| Val -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 298526.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 12652.8 | |
| All* | Total formula weight | 311179.5 |






