5C8D

Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Light-dependent transcriptional regulator CarH	polymer	305	33323.3	8	UniProt (Q746J7) Pfam (PF13411) Pfam (PF02607)	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
2	I, K, M, O, Q... (A, B, C, D, E...)	COBALAMIN	non-polymer		1330.4	8	Chemie (B12)
3	J, L, N, P, R... (A, B, C, D, E...)	5'-DEOXYADENOSINE	non-polymer		251.2	8	Chemie (5AD)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 285 (UniProt: Q746J7)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	266586.0
Non-Polymers*	Number of molecules	16
	Total formula weight	12652.8
All*	Total formula weight	279238.8

*Water molecules are not included.