5C8D

Crystal structure of full-length Thermus thermophilus CarH bound to adenosylcobalamin (dark state)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E... (A, B, C, D, E...)	Light-dependent transcriptional regulator CarH	polymer	305	33323.3	8	UniProt (Q746J7)	Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
2	I, K, M, O, Q... (A, B, C, D, E...)	COBALAMIN	non-polymer		1330.4	8	Chemie (B12)
3	J, L, N, P, R... (A, B, C, D, E...)	5'-DEOXYADENOSINE	non-polymer		251.2	8	Chemie (5AD) PubChem (16725083) PubChem (142) PubChem (71678) PubChem (23638944) PubChem (439182) PubChem (25201172) PubChem (25796474) PubChem (25796475) PubChem (40467848) PubChem (23615209) PubChem (449044) PubChem (40467849) PubChem (1277776) PubChem (57115448) PubChem (59731278) PubChem (6398669) PubChem (6928544) PubChem (90321697) PubChem (676784) PubChem (12827542) PubChem (6541038) PubChem (121275112) PubChem (124363198) PubChem (133636852) PubChem (140689696) PubChem (142801875) PubChem (142801934)

Sequence modifications

A, B, C, D, E, F, G, H: 1 - 285 (UniProt: Q746J7)

PDB	External Database	Details
Met -19	-	initiating methionine
Gly -18	-	expression tag
Ser -17	-	expression tag
Ser -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
Ser -9	-	expression tag
Ser -8	-	expression tag
Gly -7	-	expression tag
Leu -6	-	expression tag
Val -5	-	expression tag
Pro -4	-	expression tag
Arg -3	-	expression tag
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	266586.0
Non-Polymers*	Number of molecules	16
	Total formula weight	12652.8
All*	Total formula weight	279238.8

*Water molecules are not included.