5C7X
Crystal structure of MOR04357, a neutralizing anti-human GM-CSF antibody Fab fragment in complex with human GM-CSF
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Granulocyte-macrophage colony-stimulating factor | polymer | 127 | 14492.5 | 2 | UniProt (P04141) Pfam (PF01109) | Homo sapiens (Human) | GM-CSF,Colony-stimulating factor,CSF,Molgramostin,Sargramostim |
| 2 | C, E (H, M) | Immunglobulin G1 Fab fragment, heavy chain | polymer | 238 | 25458.3 | 2 | Homo sapiens (Human) | ||
| 3 | D, F (L, N) | Immunglobulin G1 Fab fragment, light chain | polymer | 209 | 22229.7 | 2 | Homo sapiens (Human) | ||
| 4 | G, H (H) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 5 | I, K, L (L, M, N) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 3 | Chemie (PEG) | |||
| 6 | J (L) | 1-(2-METHOXY-ETHOXY)-2-{2-[2-(2-METHOXY-ETHOXY]-ETHOXY}-ETHANE | non-polymer | 266.3 | 1 | Chemie (PG6) | |||
| 7 | M, N, O, P, Q... (A, B, H, L, M...) | water | water | 18.0 | 34 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 124361.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 885.0 | |
| All* | Total formula weight | 125246.0 |
