5C71
The structure of Aspergillus oryzae a-glucuronidase complexed with glycyrrhetinic acid monoglucuronide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Glucuronidase | polymer | 637 | 71245.4 | 4 | UniProt (A7XS03) | Aspergillus oryzae | |
| 2 | E, G (A, C) | (3BETA,5BETA,14BETA)-3-HYDROXY-11-OXOOLEAN-12-EN-29-OIC ACID | non-polymer | 470.7 | 2 | Chemie (CBW) PubChem (16219451) PubChem (16757767) PubChem (16759277) PubChem (17751012) PubChem (18530175) PubChem (176519885) PubChem (23426892) PubChem (24126417) PubChem (24728667) PubChem (24840718) PubChem (24840722) PubChem (25796773) PubChem (42051909) PubChem (73398) PubChem (18526330) PubChem (21115234) PubChem (49828956) PubChem (125828) PubChem (28094590) PubChem (54084031) PubChem (54084032) PubChem (56609457) PubChem (44435791) PubChem (59271691) PubChem (59799942) PubChem (59799943) PubChem (440167) PubChem (67197437) PubChem (67523993) PubChem (67591316) PubChem (68265830) PubChem (53393510) PubChem (72947821) PubChem (86574228) PubChem (68219106) PubChem (70532701) PubChem (89950111) PubChem (89950117) PubChem (3230) PubChem (10114) PubChem (90658335) PubChem (112111) PubChem (5317760) PubChem (97182165) PubChem (98145201) PubChem (6604622) PubChem (124351362) PubChem (5702158) PubChem (5702287) PubChem (124721092) PubChem (129121397) PubChem (129460562) PubChem (129689801) PubChem (98092677) PubChem (98092680) PubChem (98092682) PubChem (98092683) PubChem (7067783) PubChem (7067786) PubChem (7067788) PubChem (7067790) PubChem (121334457) PubChem (11870318) PubChem (9826000) PubChem (9897771) PubChem (12310273) PubChem (124518075) PubChem (11751767) PubChem (11870316) PubChem (11870320) PubChem (11870322) PubChem (11870421) PubChem (11870423) PubChem (11870425) PubChem (124721091) PubChem (12097316) PubChem (12193680) PubChem (12310260) PubChem (12310262) PubChem (12310272) PubChem (12310275) PubChem (12310280) PubChem (12310282) PubChem (155900334) PubChem (162991546) PubChem (163781710) PubChem (129360478) PubChem (129447954) PubChem (133109089) PubChem (133568304) PubChem (133612083) PubChem (133685580) PubChem (134689057) PubChem (154515951) PubChem (156280553) PubChem (162991547) PubChem (162991548) PubChem (162991549) PubChem (162991550) PubChem (162991551) PubChem (162991552) PubChem (162991553) PubChem (162991554) PubChem (162991555) PubChem (170851295) PubChem (170924268) PubChem (171352479) | |||
| 3 | F, H (A, C) | alpha-D-glucopyranuronic acid | non-polymer | 194.1 | 2 | Chemie (GCU) | |||
| 4 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 180 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 604 (UniProt: A7XS03)
| PDB | External Database | Details |
|---|---|---|
| Met -32 | - | initiating methionine |
| Gly -31 | - | expression tag |
| Ser -30 | - | expression tag |
| Ser -29 | - | expression tag |
| His -28 | - | expression tag |
| His -27 | - | expression tag |
| His -26 | - | expression tag |
| His -25 | - | expression tag |
| His -24 | - | expression tag |
| His -23 | - | expression tag |
| Ser -22 | - | expression tag |
| Ser -21 | - | expression tag |
| Gly -20 | - | expression tag |
| Leu -19 | - | expression tag |
| Val -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Arg -16 | - | expression tag |
| Gly -15 | - | expression tag |
| Ser -14 | - | expression tag |
| His -13 | - | expression tag |
| Met -12 | - | expression tag |
| Ala -11 | - | expression tag |
| Ser -10 | - | expression tag |
| Met -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Gly -7 | - | expression tag |
| Gly -6 | - | expression tag |
| Gln -5 | - | expression tag |
| Gln -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Arg -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Asp 414 | Glu 414 | engineered mutation |
| Asp 505 | Glu 505 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 284981.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1329.6 | |
| All* | Total formula weight | 286311.1 |
