5C6T
Crystal structure of HCMV glycoprotein B in complex with 1G2 Fab
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Envelope glycoprotein B | polymer | 636 | 73034.3 | 1 | UniProt (P13201) Pfam (PF17416) Pfam (PF17417) Pfam (PF00606) In PDB | Human cytomegalovirus (HHV-5) | gB |
2 | H | 1G2 Fab heavy chain | polymer | 233 | 25302.3 | 1 | Homo sapiens | ||
3 | L | 1G2 Fab light chain | polymer | 214 | 22853.1 | 1 | Homo sapiens | ||
4 | B | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
5 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 8 | Chemie (NAG) | |||
6 | A | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) |
Sequence modifications
A: 87 - 698 (UniProt: P13201)
PDB | External Database | Details |
---|---|---|
Met 63 | - | expression tag |
Glu 64 | - | expression tag |
Ser 65 | - | expression tag |
Arg 66 | - | expression tag |
Ile 67 | - | expression tag |
Trp 68 | - | expression tag |
Cys 69 | - | expression tag |
Leu 70 | - | expression tag |
Val 71 | - | expression tag |
Val 72 | - | expression tag |
Cys 73 | - | expression tag |
Val 74 | - | expression tag |
Asn 75 | - | expression tag |
Leu 76 | - | expression tag |
Cys 77 | - | expression tag |
Ile 78 | - | expression tag |
Val 79 | - | expression tag |
Cys 80 | - | expression tag |
Leu 81 | - | expression tag |
Gly 82 | - | expression tag |
Ala 83 | - | expression tag |
Ala 84 | - | expression tag |
Val 85 | - | expression tag |
Ser 86 | - | expression tag |
His 156 | Ile 156 | engineered mutation |
Arg 157 | His 157 | engineered mutation |
Asn 240 | Trp 240 | engineered mutation |
Thr 242 | Tyr 242 | engineered mutation |
Ser 246 | Cys 246 | engineered mutation |
Ser 457 | Arg 457 | engineered mutation |
Ser 460 | Arg 460 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 121189.7 | |
Branched | Number of molecules | 1 |
Total formula weight | 424.4 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1794.0 | |
All* | Total formula weight | 123408.1 |