5C6C
PKG II's Amino Terminal Cyclic Nucleotide Binding Domain (CNB-A) in a complex with cAMP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | cGMP-dependent protein kinase 2 | polymer | 143 | 16576.9 | 2 | UniProt (Q13237) Pfam (PF00027) | Homo sapiens (Human) | cGK2,cGMP-dependent protein kinase II,cGKII |
| 2 | C, D, E, L, M... (A, B) | CADMIUM ION | non-polymer | 112.4 | 6 | Chemie (CD) | |||
| 3 | F, O (A, B) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
| 4 | G, H, I, P (A, B) | COBALT (II) ION | non-polymer | 58.9 | 4 | Chemie (CO) | |||
| 5 | J, Q (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 6 | K (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 7 | R (B) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 8 | S, T (A, B) | water | water | 18.0 | 106 | Chemie (HOH) |
Sequence modifications
A, B: 137 - 277 (UniProt: Q13237)
| PDB | External Database | Details |
|---|---|---|
| Gly 135 | - | expression tag |
| Ser 136 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 33153.9 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1733.8 | |
| All* | Total formula weight | 34887.7 |
