5C4E
Crystal structure of GTB + UDP-Glc + H-antigen acceptor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 298 | 34656.0 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (Human) | Fucosylglycoprotein 3-alpha-galactosyltransferase,Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,Histo-blood group A transferase,A transferase,Histo-blood group B transferase,B transferase,NAGAT |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 1 | Chemie (UDP) | |||
| 4 | D (A) | hexyl 2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-galactopyranoside | non-polymer | 410.5 | 1 | Chemie (4YA) | |||
| 5 | E (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 6 | F (A) | water | water | 18.0 | 275 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 176 | Arg 176 | engineered mutation |
| Ser 235 | Gly 235 | engineered mutation |
| Met 266 | Leu 266 | engineered mutation |
| Ala 268 | Gly 268 | engineered mutation |
| Glu 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34656.0 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 989.7 | |
| All* | Total formula weight | 35645.7 |
