5C48
Crystal structure of GTB + UDP-C-Gal + DI
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Histo-blood group ABO system transferase | polymer | 298 | 34656.0 | 1 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (Human) | Fucosylglycoprotein 3-alpha-galactosyltransferase,Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,Histo-blood group A transferase,A transferase,Histo-blood group B transferase,B transferase,NAGAT |
| 2 | B (A) | MANGANESE (II) ION | non-polymer | 54.9 | 1 | Chemie (MN) | |||
| 3 | C (A) | octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside | non-polymer | 422.5 | 1 | Chemie (DA8) | |||
| 4 | D (A) | (((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)methyl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride | non-polymer | 564.3 | 1 | Chemie (URM) | |||
| 5 | E (A) | water | water | 18.0 | 223 | Chemie (HOH) |
Sequence modifications
A: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Gly 176 | Arg 176 | engineered mutation |
| Ser 235 | Gly 235 | engineered mutation |
| Met 266 | Leu 266 | engineered mutation |
| Ala 268 | Gly 268 | engineered mutation |
| Glu 355 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 34656.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1041.8 | |
| All* | Total formula weight | 35697.7 |
