5C47

Crystal structure of ABBB + UDP-C-Gal (long soak) + DI

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Histo-blood group ABO system transferase	polymer	298	34756.1	1	UniProt (P16442) Pfam (PF03414) In PDB	Homo sapiens (Human)	Fucosylglycoprotein 3-alpha-galactosyltransferase,Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase,Glycoprotein-fucosylgalactoside alpha-galactosyltransferase,Histo-blood group A transferase,A transferase,Histo-blood group B transferase,B transferase,NAGAT
2	A	MANGANESE (II) ION	non-polymer		54.9	1	Chemie (MN)
3	A	octyl 3-deoxy-2-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-xylo-hexopyranoside	non-polymer		422.5	1	Chemie (DA8)
4	A	2-(2-METHOXYETHOXY)ETHANOL	non-polymer		120.1	1	Chemie (PG0)
5	A	(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)methyl)phosphonic (((2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphoric) anhydride	non-polymer		564.3	1	Chemie (URM)
6		water	water		18.0	243	Chemie (HOH)

Sequence modifications

A: 64 - 354 (UniProt: P16442)

PDB	External Database	Details
Ala 58	-	expression tag
Ile 59	-	expression tag
Gly 60	-	expression tag
Glu 61	-	expression tag
Phe 62	-	expression tag
Met 63	-	expression tag
Ser 235	Gly 235	engineered mutation
Met 266	Leu 266	engineered mutation
Ala 268	Gly 268	engineered mutation
Glu 355	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	34756.1
Non-Polymers*	Number of molecules	4
	Total formula weight	1161.9
All*	Total formula weight	35918.0

*Water molecules are not included.