5C2K
Crystal structure of the fusion protein linked by RhoA and the GAP domain of MgcRacGAP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Transforming protein RhoA,Rac GTPase-activating protein 1 | polymer | 415 | 46070.9 | 1 | UniProt (P61586) UniProt (Q9H0H5) Pfam (PF00071) Pfam (PF00620) | Homo sapiens (Human) | MgcRacGAP |
| 2 | B (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 3 | C (A) | ALUMINUM FLUORIDE | non-polymer | 84.0 | 1 | Chemie (AF3) | |||
| 4 | D (A) | GUANOSINE-5'-DIPHOSPHATE | non-polymer | 443.2 | 1 | Chemie (GDP) | |||
| 5 | E (A) | water | water | 18.0 | 609 | Chemie (HOH) |
Sequence modifications
A: 1 - 193 (UniProt: P61586)
A: 208 - 408 (UniProt: Q9H0H5)
| PDB | External Database | Details |
|---|---|---|
| Gly -6 | - | expression tag |
| Ser -5 | - | expression tag |
| Ser -4 | - | expression tag |
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| Ser -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Ser 194 | - | linker |
| Gly 195 | - | linker |
| Ser 196 | - | linker |
| Ser 197 | - | linker |
| Gly 198 | - | linker |
| Ser 199 | - | linker |
| Ser 200 | - | linker |
| Gly 201 | - | linker |
| Ser 202 | - | linker |
| Ser 203 | - | linker |
| Gly 204 | - | linker |
| Ser 205 | - | linker |
| Ser 206 | - | linker |
| Gly 207 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Asp 249 | Ser 387 | engineered mutation |
| Ser 380 | Leu 518 | See Sequence details |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46070.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 551.5 | |
| All* | Total formula weight | 46622.4 |
