5C1X

Crystal structure of EV71 3C Proteinase in complex with Compound VIII

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	3C proteinase	polymer	192	21391.5	2	UniProt (A9XG43) Pfam (PF00548)	Enterovirus A71
2	C, D (A, B)	(phenylmethyl) N-[(2S)-1-oxidanylidene-1-[[(2S)-1-oxidanyl-3-[(3S)-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-3-phenyl-propan-2-yl]carbamate	non-polymer		439.5	2	Chemie (GHX)
3	E, F (A, B)	water	water		18.0	243	Chemie (HOH)

Sequence modifications

A, B: 1 - 183 (UniProt: A9XG43)

PDB	External Database	Details
Met 0	-	expression tag
Leu 184	-	expression tag
Glu 185	-	expression tag
His 186	-	expression tag
His 187	-	expression tag
His 188	-	expression tag
His 189	-	expression tag
His 190	-	expression tag
His 191	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	42783.0
Non-Polymers*	Number of molecules	2
	Total formula weight	879.0
All*	Total formula weight	43662.0

*Water molecules are not included.