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5C1R

Stereoisomer of PRPP bound in the active site of Mycobacterium tuberculosis anthranilate phosphoribosyl (AnPRT; trpD)

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Anthranilate phosphoribosyltransferasepolymer37938948.02UniProt (P9WFX5)
Pfam (PF02885)
Pfam (PF00591)
Mycobacterium tuberculosis
2C, D, G, H
(A, B)
MAGNESIUM IONnon-polymer24.34Chemie (MG)
3E, I
(A, B)
5-O-[(R)-hydroxy(phosphonooxy)phosphoryl]-1-O-phosphono-alpha-D-ribofuranosenon-polymer390.12Chemie (51N)
4F
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5J, K
(A, B)
waterwater18.0500Chemie (HOH)
Sequence modifications
A, B: 2 - 370 (UniProt: P9WFX5)
PDBExternal DatabaseDetails
Met 0-expression tag
Val 1-expression tag
Leu 371-expression tag
Glu 372-expression tag
His 373-expression tag
His 374-expression tag
His 375-expression tag
His 376-expression tag
His 377-expression tag
His 378-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight77896.0
Non-Polymers*Number of molecules7
Total formula weight969.5
All*Total formula weight78865.5
*Water molecules are not included.

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PDB entries from 2025-07-23

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