5C03
Crystal Structure of kinase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | Non-receptor tyrosine-protein kinase TYK2 | polymer | 342 | 38475.5 | 2 | UniProt (P29597) Pfam (PF07714) In PDB | Homo sapiens (Human) | |
2 | A, B | PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER | non-polymer | 523.2 | 2 | Chemie (AGS) | |||
3 | A, B | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
4 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
5 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
6 | water | water | 18.0 | 298 | Chemie (HOH) |
Sequence modifications
A, B: 556 - 871 (UniProt: P29597)
PDB | External Database | Details |
---|---|---|
Met 530 | - | expression tag |
Ser 531 | - | expression tag |
Tyr 532 | - | expression tag |
Tyr 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
His 538 | - | expression tag |
His 539 | - | expression tag |
Asp 540 | - | expression tag |
Tyr 541 | - | expression tag |
Asp 542 | - | expression tag |
Ile 543 | - | expression tag |
Pro 544 | - | expression tag |
Thr 545 | - | expression tag |
Thr 546 | - | expression tag |
Glu 547 | - | expression tag |
Asn 548 | - | expression tag |
Leu 549 | - | expression tag |
Tyr 550 | - | expression tag |
Phe 551 | - | expression tag |
Gln 552 | - | expression tag |
Gly 553 | - | expression tag |
Ala 554 | - | expression tag |
Met 555 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 76951.1 | |
Non-Polymers* | Number of molecules | 15 |
Total formula weight | 1928.0 | |
All* | Total formula weight | 78879.0 |