5BWL
Crystal Structure of SIRT5 in Complex with a Coumarin-Labelled Succinyl Peptide
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | NAD-dependent protein deacylase sirtuin-5, mitochondrial | polymer | 290 | 31584.9 | 1 | UniProt (Q9NXA8) Pfam (PF02146) In PDB | Homo sapiens (Human) | Regulatory protein SIR2 homolog 5,SIR2-like protein 5 |
2 | B | Coumarin-labelled succinyl peptide | polymer | 3 | 416.5 | 1 | synthetic construct | ||
3 | A | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
4 | B | 7-AMINO-4-METHYL-CHROMEN-2-ONE | non-polymer | 175.2 | 1 | Chemie (MCM) | |||
5 | water | water | 18.0 | 376 | Chemie (HOH) |
Sequence modifications
A: 33 - 302 (UniProt: Q9NXA8)
PDB | External Database | Details |
---|---|---|
Met 13 | - | expression tag |
Gly 14 | - | expression tag |
Ser 15 | - | expression tag |
Ser 16 | - | expression tag |
His 17 | - | expression tag |
His 18 | - | expression tag |
His 19 | - | expression tag |
His 20 | - | expression tag |
His 21 | - | expression tag |
His 22 | - | expression tag |
Ser 23 | - | expression tag |
Ser 24 | - | expression tag |
Gly 25 | - | expression tag |
Leu 26 | - | expression tag |
Val 27 | - | expression tag |
Pro 28 | - | expression tag |
Arg 29 | - | expression tag |
Gly 30 | - | expression tag |
Ser 31 | - | expression tag |
His 32 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 32001.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 240.6 | |
All* | Total formula weight | 32242.0 |