5BUH
Influenza PB2 bound to a hydroxymethyl azaindole inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Polymerase basic protein 2 | polymer | 169 | 19174.3 | 1 | UniProt (Q30NP1) Pfam (PF00604) In PDB | Influenza A virus | RNA-directed RNA polymerase subunit P3 |
| 2 | A | N-[(1R,3S)-3-({5-fluoro-2-[5-fluoro-2-(hydroxymethyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]pyrimidin-4-yl}amino)cyclohexyl]pyrrolidine-1-carboxamide | non-polymer | 471.5 | 1 | Chemie (4V7) | |||
| 3 | water | water | 18.0 | 27 | Chemie (HOH) |
Sequence modifications
A: 18 - 183 (UniProt: Q30NP1)
| PDB | External Database | Details |
|---|---|---|
| Gly 15 | - | cloning artifact |
| His 16 | - | cloning artifact |
| Met 17 | - | cloning artifact |
| Lys 89 | Arg 389 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 19174.3 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 471.5 | |
| All* | Total formula weight | 19645.8 |
