5BUE
ERK2 complexed with N-benzylpyridone tetrahydroazaindazole
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Mitogen-activated protein kinase 1 | polymer | 361 | 41467.6 | 1 | UniProt (P28482) Pfam (PF00069) | Homo sapiens (Human) | MAPK 1,ERT1,Extracellular signal-regulated kinase 2,ERK-2,MAP kinase isoform p42,p42-MAPK,Mitogen-activated protein kinase 2,MAPK 2 |
| 2 | B (A) | 1-benzyl-4-[3-(pyridin-4-yl)-2,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl]pyridin-2(1H)-one | non-polymer | 383.4 | 1 | Chemie (4V8) | |||
| 3 | C (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | D (A) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A: 0 - 358 (UniProt: P28482)
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Pro -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 41467.6 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.1 | |
| All* | Total formula weight | 41909.8 |
