5BTV
Crystal structure of human 14-3-3 sigma in complex with a Tau-protein peptide surrounding pS324
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 14-3-3 protein sigma | polymer | 235 | 26475.8 | 1 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (Human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B (P) | Microtubule-associated protein tau - peptide pS324 | polymer | 4 | 412.3 | 1 | UniProt (by SIFTS) (P10636) | Homo sapiens | |
| 3 | C, E (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | D (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 5 | F (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | G, H (A, P) | water | water | 18.0 | 316 | Chemie (HOH) |
Sequence modifications
A: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Cys 68 | Lys 68 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 26888.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 124.1 | |
| All* | Total formula weight | 27012.3 |
