5BQ8
Crystal structure of Norrin, a Wnt signalling activator, Crystal Form II
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Norrin | polymer | 122 | 13668.8 | 2 | UniProt (Q00604) Pfam (PF00007) | Homo sapiens (Human) | Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein |
| 2 | B (B) | Norrin | polymer | 122 | 13695.8 | 1 | UniProt (Q00604) Pfam (PF00007) | Homo sapiens (Human) | Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein |
| 3 | D (D) | Norrin | polymer | 122 | 13722.9 | 1 | UniProt (Q00604) Pfam (PF00007) | Homo sapiens (Human) | Norrie disease protein,X-linked exudative vitreoretinopathy 2 protein |
| 4 | E, F, H (B, C, D) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | G (D) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | I, J, K, L (A, B, C, D) | water | water | 18.0 | 122 | Chemie (HOH) |
Sequence modifications
A, C: 25 - 133 (UniProt: Q00604)
B: 25 - 133 (UniProt: Q00604)
D: 25 - 133 (UniProt: Q00604)
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 134 | - | expression tag |
| Thr 135 | - | expression tag |
| Glu 136 | - | expression tag |
| Thr 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Gln 139 | - | expression tag |
| Val 140 | - | expression tag |
| Ala 141 | - | expression tag |
| Pro 142 | - | expression tag |
| Ala 143 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 134 | - | expression tag |
| Thr 135 | - | expression tag |
| Glu 136 | - | expression tag |
| Thr 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Gln 139 | - | expression tag |
| Val 140 | - | expression tag |
| Ala 141 | - | expression tag |
| Pro 142 | - | expression tag |
| Ala 143 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 22 | - | expression tag |
| Pro 23 | - | expression tag |
| Gly 24 | - | expression tag |
| Gly 134 | - | expression tag |
| Thr 135 | - | expression tag |
| Glu 136 | - | expression tag |
| Thr 137 | - | expression tag |
| Ser 138 | - | expression tag |
| Gln 139 | - | expression tag |
| Val 140 | - | expression tag |
| Ala 141 | - | expression tag |
| Pro 142 | - | expression tag |
| Ala 143 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 54756.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 212.5 | |
| All* | Total formula weight | 54968.8 |
