5BPM
Crystal structure of unhydrolyzed ATP bound human Hsp70 NBD double mutant E268Q+R272K.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Heat shock 70 kDa protein 1A | polymer | 388 | 42729.4 | 1 | UniProt (P0DMV8) Pfam (PF00012) | Homo sapiens (Human) | Heat shock 70 kDa protein 1,HSP70.1 |
| 2 | B (A) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 1 | Chemie (ATP) | |||
| 3 | C, F (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | D (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 5 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | G (A) | water | water | 18.0 | 418 | Chemie (HOH) |
Sequence modifications
A: 1 - 388 (UniProt: P0DMV8)
| PDB | External Database | Details |
|---|---|---|
| Gln 268 | Glu 268 | engineered mutation |
| Lys 272 | Arg 272 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42729.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 625.4 | |
| All* | Total formula weight | 43354.7 |
