5BP7

Crystal structure of SAM-dependent methyltransferase from Geobacter sulfurreducens in complex with S-Adenosyl-L-homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C (A, B, C)	SAM-dependent methyltransferase	polymer	271	30170.9	3	UniProt (Q74AD5) Pfam (PF13847)	Geobacter sulfurreducens
2	D, F, G (A, B, C)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	3	Chemie (SAH)
3	E, H (A, C)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	I, J, K (A, B, C)	water	water		18.0	418	Chemie (HOH)

Sequence modifications

A, B, C: 3 - 249 (UniProt: Q74AD5)

PDB	External Database	Details
Mse -21	-	initiating methionine
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag
Mse 1	-	expression tag
Leu 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	90512.7
Non-Polymers*	Number of molecules	5
	Total formula weight	1224.1
All*	Total formula weight	91736.8

*Water molecules are not included.