5B8H

Crystal Structure of Type III pantothenate kinase (PanK III) from Burkholderia cenocepacia complexed with pantothenate, imidodiphosphate, and AMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	Type III pantothenate kinase	polymer	290	30746.0	2	UniProt (B4E9P3) Pfam (PF03309) In PDB	Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610)	PanK-III,Pantothenic acid kinase
2	A, B	IMIDODIPHOSPHORIC ACID	non-polymer		177.0	2	Chemie (2PN)
3	A, B	PANTOTHENOIC ACID	non-polymer		219.2	2	Chemie (PAU)
4	A, B	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
5	A	ADENOSINE MONOPHOSPHATE	non-polymer		347.2	1	Chemie (AMP)
6		water	water		18.0	222	Chemie (HOH)

Sequence modifications

A, B: 1 - 266 (UniProt: B4E9P3)

PDB	External Database	Details
Mse -23	-	initiating methionine
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61491.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1263.8
All*	Total formula weight	62755.7

*Water molecules are not included.