5B72
Crystal structure of bovine lactoperoxidase with a broken covalent bond between Glu258 and heme moiety at 1.98 A resolution.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lactoperoxidase | polymer | 595 | 67740.2 | 1 | UniProt (P80025) Pfam (PF03098) | Bos taurus (Bovine) | LPO |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | C (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 4 | D (A) | 1-(OXIDOSULFANYL)METHANAMINE | non-polymer | 79.1 | 1 | Chemie (OSM) | |||
| 5 | E, F, G, N, O... (A) | IODIDE ION | non-polymer | 126.9 | 9 | Chemie (IOD) | |||
| 6 | H, I (A) | TRIETHYLENE GLYCOL | non-polymer | 150.2 | 2 | Chemie (PGE) | |||
| 7 | J, K, L (A) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 3 | Chemie (NAG) | |||
| 8 | M (A) | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
| 9 | T (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 10 | U (A) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence modifications
A: 1 - 595 (UniProt: P80025)
| PDB | External Database | Details |
|---|---|---|
| Ser 220 | Trp 337 | engineered mutation |
| Ser 254 | Phe 371 | engineered mutation |
| Lys 410 | Asp 527 | engineered mutation |
| Met 547 | Val 664 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 67740.2 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 2937.9 | |
| All* | Total formula weight | 71102.5 |
