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5B6F

Crystal structure of the Fab fragment of an anti-Leukotriene C4 monoclonal antibody complexed with LTC4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C, E, G
(A, C, E, G)
anti-leukotriene C4 monoclonal antibody immunoglobulin kappa light chainpolymer23826369.74Mus musculus
2B, D, F, H
(B, D, F, H)
anti-leukotriene C4 monoclonal antibody immunoglobulin gamma1 heavy chainpolymer23725795.34Mus musculus
3I, L, P, T
(A, C, E, G)
(5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-( 2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acidnon-polymer625.84Chemie (LTX)
4J, M, N, Q, S...
(B, C, D, E, G...)
SULFATE IONnon-polymer96.16Chemie (SO4)
5K, O, R, V
(B, D, F, H)
2-(N-MORPHOLINO)-ETHANESULFONIC ACIDnon-polymer195.24Chemie (MES)
6AA, BA, CA, DA, W...
(E, F, G, H, A...)
waterwater18.01259Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains8
Total formula weight208659.7
Non-Polymers*Number of molecules14
Total formula weight3860.4
All*Total formula weight212520.1
*Water molecules are not included.

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PDB entries from 2025-06-18

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