5AX9
Crystal structure of the kinase domain of human TRAF2 and NCK-interacting protein kinase in complex with compund 9
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C | TRAF2 and NCK-interacting protein kinase | polymer | 308 | 35076.3 | 3 | UniProt (Q9UKE5) Pfam (PF00069) In PDB | Homo sapiens (Human) | |
| 2 | A, B, C | 4-methoxy-3-[2-[(3-methoxy-4-morpholin-4-yl-phenyl)amino]pyridin-4-yl]benzenecarbonitrile | non-polymer | 416.5 | 3 | Chemie (4KT) | |||
| 3 | A, B | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 4 | water | water | 18.0 | 107 | Chemie (HOH) |
Sequence modifications
A, B, C: 11 - 314 (UniProt: Q9UKE5)
| PDB | External Database | Details |
|---|---|---|
| Gly 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Gly 9 | - | expression tag |
| Ala 10 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 105229.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1441.5 | |
| All* | Total formula weight | 106670.5 |
