5ARF
SMYD2 in complex with small molecule inhibitor compound-2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | N-LYSINE METHYLTRANSFERASE SMYD2 | polymer | 433 | 49686.0 | 1 | UniProt (Q9NRG4) Pfam (PF00856) Pfam (PF01753) | HOMO SAPIENS (HUMAN) | |
| 2 | B (A) | N-[3-(4-CHLOROPHENYL)-1-{N'-CYANO-N-[3-(DIFLUOROMETHOXY)PHENYL]CARBAMIMIDOYL}-4,5-DIHYDRO-1H- PYRAZOL-4-YL]-N-ETHYL-2-HYDROXYACETAMIDE | non-polymer | 490.9 | 1 | Chemie (I9H) | |||
| 3 | C (A) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 1 | Chemie (SAM) | |||
| 4 | D, E, F (A) | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) | |||
| 5 | G (A) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A: 2 - 433 (UniProt: Q9NRG4)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 49686.0 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1085.6 | |
| All* | Total formula weight | 50771.5 |
