5ARB
Cooperative bio-metallic selectivity in a tailored protease enables creation of a C-C cross-coupling Heckase
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | SUBTILISIN SAVINASE | polymer | 269 | 26708.4 | 1 | UniProt (P29600) Pfam (PF00082) In PDB | BACILLUS LENTUS | ALKALINE PROTEASE, SUBTILISIN |
2 | A | CALCIUM ION | non-polymer | 40.1 | 1 | Chemie (CA) | |||
3 | A | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
4 | A | 5-methyl-2-(5-methylpyridin-2-yl)pyridine | non-polymer | 184.2 | 1 | Chemie (EI3) | |||
5 | A | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
6 | A | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
7 | water | water | 18.0 | 348 | Chemie (HOH) |
Sequence modifications
A: 1 - 275 (UniProt: P29600)
PDB | External Database | Details |
---|---|---|
Cys 217 | Leu 211 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 26708.4 | |
Non-Polymers* | Number of molecules | 7 |
Total formula weight | 632.1 | |
All* | Total formula weight | 27340.5 |