5APH

Ligand complex of RORg LBD

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	NUCLEAR RECEPTOR ROR-GAMMA	polymer	266	30901.4	1	UniProt (P51449) Pfam (PF00104) In PDB	HOMO SAPIENS (HUMAN)	NUCLEAR RECEPTOR RZR-GAMMA, NUCLEAR RECEPTOR SUBFAMILY 1 GROUP F MEMBER 3, RAR-RELATED ORPHAN RECEPTOR C, RETINOID-RELATED ORPHAN RECEPTOR-GAMMA, RORG
2	C	NUCLEAR RECEPTOR COACTIVATOR 2	polymer	12	1492.8	1	UniProt (E7EWM1) UniProt (by SIFTS) (Q15596) In PDB	HOMO SAPIENS (HUMAN)
3	A	N-(2-FLUOROPHENYL)-4-[(4-FLUOROPHENYL)SULFONYL]-2,3,4,5-TETRAHYDRO-1,4-BENZOXAZEPIN-6-AMINE	non-polymer		416.4	1	Chemie (VYI)
4	A	DIMETHYL SULFOXIDE	non-polymer		78.1	1	Chemie (DMS)
5		water	water		18.0	297	Chemie (HOH)

Sequence modifications

A: 265 - 507 (UniProt: P51449)

PDB	External Database	Details
His 244	-	expression tag
Asn 245	-	expression tag
His 246	-	expression tag
Asn 247	-	expression tag
His 248	-	expression tag
Asn 249	-	expression tag
His 250	-	expression tag
Asn 251	-	expression tag
His 252	-	expression tag
Asn 253	-	expression tag
His 254	-	expression tag
Asn 255	-	expression tag
Gly 256	-	expression tag
Gly 257	-	expression tag
Glu 258	-	expression tag
Asn 259	-	expression tag
Leu 260	-	expression tag
Tyr 261	-	expression tag
Phe 262	-	expression tag
Gln 263	-	expression tag
Gly 264	-	expression tag
Gly 508	-	expression tag
Gly 509	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	32394.2
Non-Polymers*	Number of molecules	2
	Total formula weight	494.6
All*	Total formula weight	32888.8

*Water molecules are not included.