5APA

Crystal structure of human aspartate beta-hydroxylase isoform a

Replaces:  3RCQ

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE	polymer	220	25642.2	1	UniProt (Q12797) Pfam (PF05118) In PDB	HOMO SAPIENS (HUMAN)	ASPARTATE BETA-HYDROXYLASE, ASP BETA-HYDROXYLASE, PEPTIDE-A SPARTATE BETA-DIOXYGENASE, ASPARTATE BETA-HYDROXYLASE
2	A	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
3	A	(2S)-2-hydroxybutanedioic acid	non-polymer		134.1	1	Chemie (LMR)
4	A	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
5		water	water		18.0	139	Chemie (HOH)

Sequence modifications

A: 562 - 758 (UniProt: Q12797)

PDB	External Database	Details
Met 539	-	expression tag
His 540	-	expression tag
His 541	-	expression tag
His 542	-	expression tag
His 543	-	expression tag
His 544	-	expression tag
His 545	-	expression tag
Ser 546	-	expression tag
Ser 547	-	expression tag
Gly 548	-	expression tag
Val 549	-	expression tag
Asp 550	-	expression tag
Leu 551	-	expression tag
Gly 552	-	expression tag
Thr 553	-	expression tag
Glu 554	-	expression tag
Asn 555	-	expression tag
Leu 556	-	expression tag
Tyr 557	-	expression tag
Phe 558	-	expression tag
Gln 559	-	expression tag
Ser 560	-	expression tag
Met 561	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	25642.2
Non-Polymers*	Number of molecules	3
	Total formula weight	254.8
All*	Total formula weight	25897.1

*Water molecules are not included.