5ANQ
inhibitors of JumonjiC domain-containing histone demethylases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | LYSINE-SPECIFIC DEMETHYLASE 4A | polymer | 359 | 41767.5 | 2 | UniProt (O75164) Pfam (PF02375) Pfam (PF02373) | HOMO SAPIENS (HUMAN) | JMJC DOMAIN-CONTAINING HISTONE DEMETHYLATION PROTEIN 3A, JUMONJI DOMAIN-CONTAINING PROTEIN 2A |
| 2 | C, I (A, B) | 2-{2-[(pyridin-3-ylmethyl)amino]pyrimidin-4-yl}pyridine-4-carboxylic acid | non-polymer | 307.3 | 2 | Chemie (5YQ) | |||
| 3 | D, J (A, B) | FE (II) ION | non-polymer | 55.8 | 2 | Chemie (FE2) | |||
| 4 | E, F, K, L (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | G, M (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 6 | H, N, O, P (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 7 | Q, R (A, B) | water | water | 18.0 | 351 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 83535.1 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1383.2 | |
| All* | Total formula weight | 84918.3 |
