Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | FIBROBLAST GROWTH FACTOR RECEPTOR 1 | polymer | 310 | 35340.7 | 2 | UniProt (P11362) Pfam (PF07714) | HOMO SAPIENS (HUMAN) | FGFR-1, BASIC FIBROBLAST GROWTH FACTOR RECEPTOR 1, BFGFR, BFGF-R-1, FMS-LIKE TYROSINE KINASE 2, FLT-2, N-SAM, PROTO-ONCOGENE C-FGR, FIBROBLAST GROWTH FACTOR 1 |
| 2 | C, F (A, B) | 4-amino-5-fluoro-3-[5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]quinolin-2(1H)-one | non-polymer | 392.4 | 2 | Chemie (38O) | |||
| 3 | D, E, G (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | H, I (A, B) | water | water | 18.0 | 217 | Chemie (HOH) |
Sequence modifications
A, B: 458 - 765 (UniProt: P11362)
| PDB | External Database | Details |
|---|---|---|
| Met 456 | - | expression tag |
| Val 457 | - | expression tag |
| Ala 488 | Cys 488 | conflict |
| Met 561 | Val 561 | engineered mutation |
| Ser 584 | Cys 584 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 70681.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 891.2 | |
| All* | Total formula weight | 71572.6 |
