5AJZ
Human PFKFB3 in complex with an indole inhibitor 5
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | 6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE 3 | polymer | 520 | 59694.1 | 1 | UniProt (Q16875) Pfam (PF01591) Pfam (PF00300) In PDB | HOMO SAPIENS (HUMAN) | 6PF-2-K/FRU-2,6-P2ASE 3,PFK/FBPASE 3,6PF-2-K/FRU-2,6-P2ASE BRAIN/PLACENTA-TYPE ISOZYME, RENAL CARCINOMA ANTIGEN NY-REN-56, IPFK-2, PFKFB3 |
| 2 | A | PHOSPHONIC ACID | non-polymer | 82.0 | 1 | Chemie (PHS) | |||
| 3 | A | 6-O-phosphono-beta-D-fructofuranose | non-polymer | 260.1 | 1 | Chemie (F6P) | |||
| 4 | A | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | A | 2-azanyl-N-[4-[(3-cyano-1H-indol-5-yl)oxy]phenyl]ethanamide | non-polymer | 306.3 | 1 | Chemie (MJP) | |||
| 6 | water | water | 18.0 | 276 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59694.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 743.4 | |
| All* | Total formula weight | 60437.6 |
