5AJV
Human PFKFB3 in complex with an indole inhibitor 1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (B) | HUMAN PFKFB3 | polymer | 520 | 59694.1 | 1 | UniProt (Q16875) Pfam (PF01591) Pfam (PF00300) | HOMO SAPIENS (HUMAN) | |
| 2 | B, C, D (B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) PubChem (1061) | |||
| 3 | E (B) | (2S)-2-amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxy-propanamide | non-polymer | 351.4 | 1 | Chemie (8R2) | |||
| 4 | F (B) | 2,6-di-O-phosphono-beta-D-fructofuranose | non-polymer | 340.1 | 1 | Chemie (FDP) PubChem (483) PubChem (5460366) PubChem (9949812) PubChem (45109803) PubChem (50990584) PubChem (105021) PubChem (15764443) PubChem (124519606) PubChem (124519607) PubChem (124931522) PubChem (137794960) PubChem (162979383) | |||
| 5 | G (B) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 59694.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 976.4 | |
| All* | Total formula weight | 60670.5 |
