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5AJV

Human PFKFB3 in complex with an indole inhibitor 1

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1BHUMAN PFKFB3polymer52059694.11UniProt (Q16875)
Pfam (PF01591)
Pfam (PF00300)
In PDB
HOMO SAPIENS (HUMAN)
2BPHOSPHATE IONnon-polymer95.03Chemie (PO4)
3B(2S)-2-amino-N-[4-[(2-amino-3-cyano-1H-indol-5-yl)oxy]phenyl]-3-hydroxy-propanamidenon-polymer351.41Chemie (8R2)
4B2,6-di-O-phosphono-beta-D-fructofuranosenon-polymer340.11Chemie (FDP)
5waterwater18.019Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight59694.1
Non-Polymers*Number of molecules5
Total formula weight976.4
All*Total formula weight60670.5
*Water molecules are not included.

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PDB entries from 2024-06-12

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