5AIZ
The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T-cell development and leukemia
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ZINC FINGER MIZ DOMAIN-CONTAINING PROTEIN 1 | polymer | 124 | 14227.6 | 1 | UniProt (Q9ULJ6) Pfam (PF18028) | HOMO SAPIENS (HUMAN) | PIAS-LIKE PROTEIN ZIMP10, RETINOIC ACID-INDUCED PROTEIN 17, ZMIZ1 N-TERMINAL DOMAIN |
| 2 | B (A) | UNKNOWN ATOM OR ION | non-polymer | 1 | Chemie (UNX) | ||||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | E (A) | water | water | 18.0 | 131 | Chemie (HOH) |
Sequence modifications
A: 1 - 118 (UniProt: Q9ULJ6)
| PDB | External Database | Details |
|---|---|---|
| Gly -5 | - | expression tag |
| Pro -4 | - | expression tag |
| Ala -3 | - | expression tag |
| Mse -2 | - | expression tag |
| Ala -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 14227.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 121.1 | |
| All* | Total formula weight | 14348.7 |
