5AIN
Varenicline Interactions at the 5HT3 Receptor Ligand Binding Site are Revealed by 5HTBP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E (A, B, C, D, E) | SOLUBLE ACETYLCHOLINE RECEPTOR | polymer | 212 | 24098.9 | 5 | UniProt (Q8WSF8) Pfam (PF02931) | APLYSIA CALIFORNICA (CALIFORNIA SEA HARE) | 5HTBP |
| 2 | F, G, H, I, J (A, B, C, D, E) | VARENICLINE | non-polymer | 211.3 | 5 | Chemie (QMR) | |||
| 3 | K, L, M, N, O (A, B, C, D, E) | water | water | 18.0 | 493 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E: 1 - 212 (UniProt: Q8WSF8)
| PDB | External Database | Details |
|---|---|---|
| Val 41 | Ala 60 | conflict |
| Arg 55 | Gln 74 | conflict |
| Glu 92 | Ser 111 | conflict |
| Val 136 | Ala 155 | conflict |
| Leu 140 | Val 159 | conflict |
| Thr 141 | Lys 160 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 120494.6 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1056.3 | |
| All* | Total formula weight | 121550.9 |
