5AF9
Thrombin in complex with 4-Methoxy-N-(2-pyridinyl)benzamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | THROMBIN HEAVY CHAIN | polymer | 258 | 29651.1 | 1 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN ALPHA |
| 2 | B (I) | HIRUDIN VARIANT-2 | polymer | 12 | 1548.6 | 1 | UniProt (P09945) | HIRUDO MEDICINALIS | |
| 3 | C (L) | THROMBIN LIGHT CHAIN | polymer | 29 | 3432.8 | 1 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II, ACTIVATION PEPTIDE FRAGMENT 1, ACTIVATION PEPTIDE FRAGMENT 2, THROMBIN ALPHA |
| 4 | D (H) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
| 5 | E, F (H) | SODIUM ION | non-polymer | 23.0 | 2 | Chemie (NA) | |||
| 6 | G, H (H) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 2 | Chemie (DMS) | |||
| 7 | I (H) | 4-methoxy-N-(pyridin-2-yl)benzamide | non-polymer | 228.2 | 1 | Chemie (SJR) | |||
| 8 | J (H) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 9 | K, L, M (H) | GLYCEROL | non-polymer | 92.1 | 3 | Chemie (GOL) | |||
| 10 | N (H) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 11 | O, P, Q, R (H, I, L) | water | water | 18.0 | 280 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 34632.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1085.0 | |
| All* | Total formula weight | 35717.5 |
