5ACA
Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | VP1 | polymer | 214 | 24160.2 | 1 | UniProt (Q1L764) Pfam (PF22663) UniProt (by SIFTS) (Q719N0) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE SAT 2 | |
| 2 | B (2) | VP2 | polymer | 207 | 23226.0 | 1 | UniProt (Q1L764) Pfam (PF00073) UniProt (by SIFTS) (Q719N0) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE SAT 2 | |
| 3 | C (3) | VP3 | polymer | 222 | 24620.3 | 1 | UniProt (Q1L764) Pfam (PF00073) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE SAT 2 | |
| 4 | D (4) | VP4 | polymer | 85 | 8836.2 | 1 | UniProt (Q1L764) Pfam (PF08935) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE SAT 2 |
Sequence modifications
1: 1 - 217 (UniProt: Q1L764)
2: 13 - 219 (UniProt: Q1L764)
| PDB | External Database | Details |
|---|---|---|
| Ala 64 | Gly 590 | conflict |
| Tyr 172 | His 695 | conflict |
| Glu 189 | Ala 712 | conflict |
| Leu 190 | Val 713 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Leu 15 | Val 100 | conflict |
| Tyr 93 | Ser 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 80842.8 | |
| All* | Total formula weight | 80842.8 |
