5AC9
Structure-based energetics of protein interfaces guide Foot-and-Mouth disease virus vaccine design
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (1) | VP1 | polymer | 208 | 22865.9 | 1 | UniProt (Q6PMW3) Pfam (PF22663) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE O | FOOT-AND-MOUTH DISEASE VIRUS |
| 2 | B (2) | VP3 | polymer | 218 | 24417.5 | 1 | UniProt (Q6PMW3) Pfam (PF00073) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE O | FOOT-AND-MOUTH DISEASE VIRUS |
| 3 | C (3) | VP2 | polymer | 220 | 23933.9 | 1 | UniProt (Q6PMW3) Pfam (PF00073) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE O | FOOT-AND-MOUTH DISEASE VIRUS |
| 4 | D (4) | VP4 | polymer | 85 | 8766.1 | 1 | UniProt (Q6PMW3) Pfam (PF08935) | FOOT-AND-MOUTH DISEASE VIRUS - TYPE O | FOOT-AND-MOUTH DISEASE VIRUS |
Sequence modifications
1: 1 - 208 (UniProt: Q6PMW3)
2: 1 - 218 (UniProt: Q6PMW3)
3: 1 - 220 (UniProt: Q6PMW3)
| PDB | External Database | Details |
|---|---|---|
| Glu 133 | Asn 857 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Tyr 93 | Ser 379 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Thr 168 | Ala 672 | conflict |
| Val 174 | Thr 678 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 79983.4 | |
| All* | Total formula weight | 79983.4 |
