5AC7

S. enterica HisA with mutations D7N, D10G, dup13-15

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase	polymer	256	27428.4	2	UniProt (A0A630AQ07) Pfam (PF00977) UniProt (by SIFTS) (P10372) In PDB	Salmonella enterica	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
2	A, B	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
3	A	SODIUM ION	non-polymer		23.0	1	Chemie (NA)
4	A, B	SULFATE ION	non-polymer		96.1	3	Chemie (SO4)
5		water	water		18.0	233	Chemie (HOH)

Sequence modifications

A, B: 1 - 245 (UniProt: A0A630AQ07)

PDB	External Database	Details
Asn 7	Asp 7	engineered mutation
Gly 10	Asp 10	engineered mutation
Val 15	-	insertion
Val 15	-	insertion
Arg 15	-	insertion
Lys 246	-	expression tag
Gly 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	54856.7
Non-Polymers*	Number of molecules	6
	Total formula weight	495.4
All*	Total formula weight	55352.1

*Water molecules are not included.