5ABW
Neutrophil elastase inhibitors for the treatment of (cardio)pulmonary diseases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | NEUTROPHIL ELASTASE | polymer | 218 | 23319.0 | 1 | UniProt (P08246) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | BONE MARROW SERINE PROTEASE, ELASTASE-2, HUMAN LEUKOCYTE ELASTASE, HLE, MEDULLASIN, PMN ELASTASE |
| 2 | B (B) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
| 3 | C (A) | 1-(3-CHLOROPHENYL)-5-(3,5-DIMETHYLISOXAZOL-4-YL)-6-METHYL-N-[4-(METHYLSULFONYL)BENZYL]-2-OXO-1,2-DIHYDROPYRIDINE-3-CARBOXAMIDE | non-polymer | 526.0 | 1 | Chemie (WQQ) | |||
| 4 | D, E, F (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 5 | G (A) | water | water | 18.0 | 363 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 23319.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 570.5 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 632.4 | |
| All* | Total formula weight | 24521.9 |
