5ABT

S.enterica HisA mutant D7N, G102A, V106M, D176A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	1-(5-PHOSPHORIBOSYL)-5-[(5-PHOSPHORIBOSYLAMINO) METHYLIDENE AMINO] IMIDAZOLE-4-CARBOXAMIDE ISOMERASE	polymer	253	27133.0	1	UniProt (V7IJE3) Pfam (PF00977) UniProt (by SIFTS) (P10372)	SALMONELLA ENTERICA	PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE, HISA
2	B (A)	[(2R,3S,4R,5R)-5-[4-aminocarbonyl-5-[(E)-[[(2R,3R,4S,5R)-3,4-bis(oxidanyl)-5-(phosphonooxymethyl)oxolan-2-yl]amino]methylideneamino]imidazol-1-yl]-3,4-bis(oxidanyl)oxolan-2-yl]methyl dihydrogen phosphate	non-polymer		577.3	1	Chemie (GUO)
3	C (A)	water	water		18.0	226	Chemie (HOH)

Sequence modifications

A: 1 - 245 (UniProt: V7IJE3)

PDB	External Database	Details
Lys 246	-	expression tag
Gly 247	-	expression tag
His 248	-	expression tag
His 249	-	expression tag
His 250	-	expression tag
His 251	-	expression tag
His 252	-	expression tag
His 253	-	expression tag
Asn 7	Asp 7	engineered mutation
Ala 102	Gly 102	engineered mutation
Met 106	Val 106	engineered mutation
Ala 176	Asp 176	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	27133.0
Non-Polymers*	Number of molecules	1
	Total formula weight	577.3
All*	Total formula weight	27710.4

*Water molecules are not included.