5AAN
Crystal structure of Drosophila NCS-1 bound to penothiazine FD44
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CG5907-PA, ISOFORM A | polymer | 187 | 21922.4 | 1 | UniProt (Q9VWX8) Pfam (PF00036) Pfam (PF13499) | DROSOPHILA MELANOGASTER (FRUIT FLY) | FREQUENIN 2 |
| 2 | B, C, D (A) | CALCIUM ION | non-polymer | 40.1 | 3 | Chemie (CA) | |||
| 3 | E (A) | N-phenothiazin-10-yl-2-piperidin-1-yl-ethanamide | non-polymer | 339.5 | 1 | Chemie (XOC) | |||
| 4 | F (A) | 2-(2-METHOXYETHOXY)ETHANOL | non-polymer | 120.1 | 1 | Chemie (PG0) | |||
| 5 | G (A) | water | water | 18.0 | 146 | Chemie (HOH) |
Sequence modifications
A: 1 - 187 (UniProt: Q9VWX8)
| PDB | External Database | Details |
|---|---|---|
| Met 178 | Ile 178 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 21922.4 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 579.8 | |
| All* | Total formula weight | 22502.3 |
