5A91
15K X-ray ligand free: Exploring the Mechanism of beta-Lactam Ring Protonation in the Class A beta-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Beta-lactamase Toho-1 | polymer | 262 | 28117.8 | 1 | UniProt (Q47066) Pfam (PF00144) Pfam (PF00905) Pfam (PF13354) UniProt (by SIFTS) (E1ANH6) In PDB | Escherichia coli | |
2 | A | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
3 | water | water | 18.0 | 442 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: Q47066)
PDB | External Database | Details |
---|---|---|
Ala 166 | Glu 169 | engineered mutation |
Asn 274 | Arg 275 | engineered mutation |
Asn 276 | Arg 277 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 28117.8 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 480.3 | |
All* | Total formula weight | 28598.1 |