5A65
Crystal structure of mouse thiamine triphosphatase in complex with thiamine diphosphate, orthophosphate and magnesium ions.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | THIAMINE TRIPHOSPHATASE | polymer | 217 | 23669.7 | 2 | UniProt (Q8JZL3) Pfam (PF01928) | MUS MUSCULUS (HOUSE MOUSE) | THTPASE |
| 2 | C, D, H, I (A, B) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 3 | E, J (A, B) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 2 | Chemie (TPP) | |||
| 4 | F, K (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 2 | Chemie (PO4) | |||
| 5 | G, L (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 6 | M, N (A, B) | water | water | 18.0 | 127 | Chemie (HOH) |
Sequence modifications
A, B: 3 - 215 (UniProt: Q8JZL3)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
| Met 1 | - | expression tag |
| Thr 2 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 47339.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1261.9 | |
| All* | Total formula weight | 48601.3 |
