5A5I
Cytochrome 2C9 P450 inhibitor complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CYTOCHROME P450 2C9 | polymer | 477 | 54322.9 | 1 | UniProt (P11712) Pfam (PF00067) | HOMO SAPIENS (HUMAN) | (R)-LIMONENE 6-MONOOXYGENASE, (S)-LIMONENE 6-MONOOXYGENASE, (S)-LIMONENE 7-MONOOXYGENASE, CYPIIC9, CYTOCHROME P-450MP, CYTOCH ROME P450 MP-4, CYTOCHROME P450 MP-8, CYTOCHROME P450 PB-1, S-MEPH ENYTOIN 4-HYDROXYLASE, CYTOCHROME 2C9 |
| 2 | B (A) | N-[4-(3-chloranyl-4-cyano-phenoxy)cyclohexyl]-1,1,1-tris(fluoranyl)methanesulfonamide | non-polymer | 382.8 | 1 | Chemie (XI1) | |||
| 3 | C (A) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 1 | Chemie (HEM) | |||
| 4 | D (A) | water | water | 18.0 | 7 | Chemie (HOH) |
Sequence modifications
A: 23 - 489 (UniProt: P11712)
| PDB | External Database | Details |
|---|---|---|
| Met 18 | - | expression tag |
| Ala 19 | - | expression tag |
| Lys 20 | - | expression tag |
| Lys 21 | - | expression tag |
| Thr 22 | - | expression tag |
| Ile 490 | - | expression tag |
| His 491 | - | expression tag |
| His 492 | - | expression tag |
| His 493 | - | expression tag |
| His 494 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54322.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 999.3 | |
| All* | Total formula weight | 55322.2 |
