5A5H
The crystal structure of the GST-like domains complex of EPRS C92SC105SC123S mutant-AIMP2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E, G | BIFUNCTIONAL GLUTAMATE/PROLINE--TRNA LIGASE | polymer | 175 | 19404.5 | 4 | UniProt (P07814) Pfam (PF21972) In PDB | HOMO SAPIENS (HUMAN) | BIFUNCTIONAL AMINOACYL-TRNA SYNTHETASE, CELL PROLIFERATION- INDUCING GENE 32 PROTEIN, GLUTAMATYL-PROLYL-TRNA SYNTHETASE, GLUTAMYL-TRNA SYNTHETASE, GLURS, PROLYL-TRNA SYNTHETASE, GLUTAMYL- PROLYL-TRNA SYNTHETASE |
2 | B, D, F, H | AMINOACYL TRNA SYNTHASE COMPLEX-INTERACTING MULTIFUNCTIONA L PROTEIN 2 | polymer | 240 | 26790.9 | 4 | UniProt (Q13155) Pfam (PF18569) Pfam (PF00043) In PDB | HOMO SAPIENS (HUMAN) | MULTISYNTHASE COMPLEX AUXILIARY COMPONENT P38, PROTEIN JTV- 1 |
3 | water | water | 18.0 | 409 | Chemie (HOH) |
Sequence modifications
A, C, E, G: 1 - 175 (UniProt: P07814)
B, D, F, H: 90 - 320 (UniProt: Q13155)
PDB | External Database | Details |
---|---|---|
Ser 92 | Cys 92 | engineered mutation |
Ser 105 | Cys 105 | engineered mutation |
Ser 123 | Cys 123 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 89 | - | expression tag |
Leu 321 | - | expression tag |
Glu 322 | - | expression tag |
His 323 | - | expression tag |
His 324 | - | expression tag |
His 325 | - | expression tag |
His 326 | - | expression tag |
His 327 | - | expression tag |
His 328 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 184781.6 | |
All* | Total formula weight | 184781.6 |