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SummaryStructural detailsExperimental detailsFunctional detailsSequence NeighborHistoryDownloads

5A5B

Structure of the 26S proteasome-Ubp6 complex

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
11PROTEASOME COMPONENT PRE3polymer21523573.61UniProt (P38624)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 1, MACROPAIN SUBUNIT PRE3, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PRE3, PROTEINASE YSCE SUBUNIT PRE3
22PROTEASOME COMPONENT PUP1polymer26128299.91UniProt (P25043)
Pfam (PF00227)
Pfam (PF12465)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 2 MACROPAIN SUBUNIT PUP1, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PUP1, PROTEINASE YSCE SUBUNIT PUP1
33PROTEASOME COMPONENT PUP3polymer20522627.81UniProt (P25451)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 3, MACROPAIN SUBUNIT PUP3, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PUP3
44PROTEASOME COMPONENT C11polymer19822545.71UniProt (P22141)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 4, MACROPAIN SUBUNIT C11, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C11, PROTEINASE YSCE SUBUNIT 11
55PROTEASOME COMPONENT PRE2polymer28731698.61UniProt (P30656)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 5, MACROPAIN SUBUNIT PRE2, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PRE2, PROTEINASE YSCE SUBUNIT PRE2
66PROTEASOME COMPONENT C5polymer24126905.11UniProt (P23724)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 6, MULTICATALYTIC ENDOPEPTIDASE
77PROTEASOME COMPONENT PRE4polymer26629471.31UniProt (P30657)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME BETA SUBUNIT 7, MACROPAIN SUBUNIT PRE4, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PRE4, PROTEINASE YSCE SUBUNIT PRE4
88UBIQUITIN CARBOXYL-TERMINAL HYDROLASE 6polymer41648825.51UniProt (P43593)
Pfam (PF00443)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
99UBIQUITIN ALDEHYDEpolymer768560.81UniProt (P0CG48)
Pfam (PF00240)
UniProt (by SIFTS) (P62987)
In PDB		HOMO SAPIENS (HUMAN)
10APROTEASOME COMPONENT C7-ALPHApolymer25228033.81UniProt (P21243)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 1, MACROPAIN SUBUNIT C7-ALPHA, MULTICATALYTIC ENDOPEPTIDASE COMPLEX C7, PROTEASOME COMPONENT Y8, PROTEINASE YSCE SUBUNIT 7, SCL1 SUPPRESSOR PROTEIN
11BPROTEASOME COMPONENT Y7polymer25027191.81UniProt (P23639)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 2, MACROPAIN SUBUNIT Y7, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y7, PROTEINASE YSCE SUBUNIT 7
12CPROTEASOME COMPONENT Y13polymer25828748.21UniProt (P23638)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 3, MACROPAIN SUBUNIT Y13, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT Y13, PROTEINASE YSCE SUBUNIT 13
13DPROTEASOME COMPONENT PRE6polymer25428478.11UniProt (P40303)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 4, MACROPAIN SUBUNIT PRE6, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PRE6, PROTEINASE YSCE SUBUNIT PRE6
14EPROTEASOME COMPONENT PUP2polymer26028649.11UniProt (P32379)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 5, MACROPAIN SUBUNIT PUP2, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PUP2, PROTEINASE YSCE SUBUNIT PUP2
15FPROTEASOME COMPONENT PRE5polymer23425634.01UniProt (P40302)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 6, MACROPAIN SUBUNIT PRE5, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT PRE5, PROTEINASE YSCE SUBUNIT PRE5
16GPROTEASOME COMPONENT C1polymer28831575.11UniProt (P21242)
Pfam (PF10584)
Pfam (PF00227)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)20S PROTEASOME ALPHA SUBUNIT 7, MACROPAIN SUBUNIT C1, MULTICATALYTIC ENDOPEPTIDASE COMPLEX SUBUNIT C1, PROTEINASE YSCE SUBUNIT 1
17H26S PROTEASE REGULATORY SUBUNIT 7 HOMOLOGpolymer46752054.91UniProt (P33299)
Pfam (PF21236)
Pfam (PF00004)
Pfam (PF17862)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT1, PROTEIN CIM5, TAT-BINDING HOMOLOG 3
18I26S PROTEASE REGULATORY SUBUNIT 4 HOMOLOGpolymer43748898.21UniProt (P40327)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT2, TAT-BINDING HOMOLOG 5
19J26S PROTEASE REGULATORY SUBUNIT 8 HOMOLOGpolymer40545342.71UniProt (Q01939)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT6, PROTEIN CIM3, PROTEIN SUG1, TAT-BINDING PROTEIN TBY1
20K26S PROTEASE REGULATORY SUBUNIT 6B HOMOLOGpolymer42847953.71UniProt (P33298)
Pfam (PF16450)
Pfam (PF00004)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT3, PROTEIN YNT1, TAT-BINDING HOMOLOG 2
21L26S PROTEASE SUBUNIT RPT4polymer43749480.11UniProt (P53549)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT4,26S PROTEASE SUBUNIT SUG2, PROTEASOMAL CAP SUBUNIT
22M26S PROTEASE REGULATORY SUBUNIT 6Apolymer43448315.71UniProt (P33297)
Pfam (PF16450)
Pfam (PF00004)
Pfam (PF17862)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPT5, TAT-BINDING PROTEIN HOMOLOG 1, TBP-1
23N26S PROTEASOME REGULATORY SUBUNIT RPN2polymer945104351.91UniProt (P32565)
Pfam (PF21505)
Pfam (PF01851)
Pfam (PF13646)
Pfam (PF18004)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN2
24O26S PROTEASOME REGULATORY SUBUNIT RPN9polymer39345839.31UniProt (Q04062)
Pfam (PF01399)
Pfam (PF18261)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN9, PROTEASOME NON-ATPASE SUBUNIT 7
25P26S PROTEASOME REGULATORY SUBUNIT RPN5polymer44551840.41UniProt (Q12250)
Pfam (PF01399)
Pfam (PF18098)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN5, PROTEASOME NON-ATPASE SUBUNIT 5
26Q26S PROTEASOME REGULATORY SUBUNIT RPN6polymer43449839.81UniProt (Q12377)
Pfam (PF18055)
Pfam (PF01399)
Pfam (PF18503)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN6, PROTEASOME NON-ATPASE SUBUNIT 4
27R26S PROTEASOME REGULATORY SUBUNIT RPN7polymer42949016.41UniProt (Q06103)
Pfam (PF10602)
Pfam (PF01399)
Pfam (PF21154)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN7
28S26S PROTEASOME REGULATORY SUBUNIT RPN3polymer52360464.61UniProt (P40016)
Pfam (PF01399)
Pfam (PF08375)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN3
29T26S PROTEASOME REGULATORY SUBUNIT RPN12polymer27431952.11UniProt (P32496)
Pfam (PF10075)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN12, NUCLEAR INTEGRITY PROTEIN 1
30U26S PROTEASOME REGULATORY SUBUNIT RPN8polymer33838365.51UniProt (Q08723)
Pfam (PF01398)
Pfam (PF13012)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN8
31V26S PROTEASOME REGULATORY SUBUNIT RPN11polymer30634442.31UniProt (P43588)
Pfam (PF01398)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN11, PROTEIN MPR1
32W26S PROTEASOME REGULATORY SUBUNIT RPN10polymer26829776.11UniProt (P38886)
Pfam (PF13519)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN10
33X26S PROTEASOME REGULATORY SUBUNIT RPN13polymer15617919.01UniProt (O13563)
Pfam (PF04683)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)RPN13, PROTEASOME NON-ATPASE SUBUNIT 13
34Y26S PROTEASOME COMPLEX SUBUNIT SEM1polymer8910397.11UniProt (O94742)
Pfam (PF05160)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)
35Z26S PROTEASOME REGULATORY SUBUNIT RPN1polymer993109601.91UniProt (P38764)
Pfam (PF17781)
Pfam (PF01851)
Pfam (PF18051)
In PDB		SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)HMG-COA REDUCTASE DEGRADATION PROTEIN 2, PROTEASOME NON-ATPASE SUBUNIT 1
Sequence modifications
5: -74 - 212 (UniProt: P30656)
PDBExternal DatabaseDetails
Arg 33Lys 108conflict
8: 97 - 499 (UniProt: P43593)
PDBExternal DatabaseDetails
Mse 85-expression tag
Gly 86-expression tag
Ser 87-expression tag
Asp 88-expression tag
Lys 89-expression tag
Ile 90-expression tag
His 91-expression tag
His 92-expression tag
His 93-expression tag
His 94-expression tag
His 95-expression tag
His 96-expression tag
Mse 500-expression tag
Val 182Ile 182conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains35
Total formula weight1366670.1
All*Total formula weight1366670.1
*Water molecules are not included.

218853

PDB entries from 2024-04-24

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